Worldwide cancer affects more than 10 million people each year. This number is expected to increase by 2.4% by 2020 to 14 million each year. Worldwide approximately 22 million people are living with cancer and nearly 7 million people die. The most common cancers affecting the world include lung, breast, colon/rectum, stomach, liver, prostate, cervical, esophageal, and bladder.

This Kalorama Information report - The World Market for Cancer Therapeutics and Biotherapeutics - focuses on several segments for cancer treatment. The report covers both currently marketed and late stage development cancer products. Revenues for each current market segment were generated using dollar and unit sales for each product.

The following approaches to cancer therapeutics are covered in the report:

• Biotherapeutics
  • Monoclonal Antibodies
  • Interleukins/ Interferons
  • Kinases and Other Treatments
• Chemotherapy
  • Alkylating Agents
  • Antimetabolites
  • Cytotoxic Agents
  • Plant Derivatives
• Hormone Therapy
  • Corticosteroids
  • Hormone Antagonists/ Antagonists
  • Aromatase Inhibitors
  • SERMS

The report includes market share by type of cancer and market share by company for each of the three major segments. It also includes statistical information for cancers by type worldwide, with special emphasis on the U.S. market. Specifically, cancers where there are current products available or are in development and/or have significant incidence/mortality rates are profiled. The market segments provide an overview, description of products on the market, list of products in late-stage development, market estimates and forecasts, and competitive analysis of leading providers. The report also includes current issues and trends affecting the industry.

A Primary Research Effort

The information for this report was gathered using both primary and secondary research including comprehensive research of secondary sources such as company literature, databases, investment reports, and medical and business journals. Telephone interviews and email correspondence were the primary method of gathering information. For the purpose of this study Kalorama Information conducted interviews with key industry officials, consultants, health care providers, and government personnel. These sources were the primary basis in gathering information specifically relating to revenue and market share data presented in this report. Specific interviews with pharmaceutical company representatives included marketing directors, division managers, and product representatives. All market data pertains to the world market at the manufacturers’ level.

Coverage of the Most Recent Product and Trends

The base year for data was 2008. Historical data was provided for the years 2004 through 2007, with forecast data provided for 2009 through 2013. Compound annual growth rates (CAGRs) are provided for the 2004-2008, 2009-2013 and 2004-2013 periods for each industry segment covered. Competitive analysis is provided for the year 2008. The forecasted market analysis for 2009-2013 was based on probability of approval and sales of products in late stage development, product marketing, and demographic trends. Some of the trends that affected this market include the following:

• Insurance and Reimbursement
• Drug Costs
• Personalized Medicine
• Alliances, Acquisitions and Licensing Agreements
• Alcohol’s Affect on Cancer Incidence
• Healthy Lifestyles Continue to Show Promise for Cancer Prevention
• Marketing and Distribution Trends
• Geographical Trends
• Elderly Clinical Trial Involvement
• Late-Stage Drug Development Trends

Profiles of Twelve Key Competitors

As part of its comprehensive coverage, the following companies are profiled:

• AstraZeneca (coverage of Arimidex, Casodex, Faslodex, Zoladex, Iressa, Nolvadex and other products)
• Biogen IDEC (coverage of Rituxan and other products)
• Bristol-Myers Squibb (coverage of Erbitux, Taxol, Ixempra, Sprycel and other products)
• Eli Lilly (coverage of Alimta, Gemzar and other products)
• Genentech (coverage of Avastin, Herceptin, Rituxan )
• Johnson & Johnson (coverage of Doxil, Velcade, Leustatin)
• Merck & Company (coverage of Zolinza and other products)
• Novartis (coverage of Femara, Gleevec/Glivec, Tasigna, Sandostatin, Proleukin, Afinitor and other products)
• Pfizer (coverage of Camptosar and Sutent)
• Roche (coverage of Xeloda, Avastin, MabThera, Herceptin, Tarceva and pipeline drugs)
• Sanofi-Aventis (coverage of Taxotere, Eloxatine and others)
• Schering-Plough (coverage of Intron A, Timodar/Temodal, Caelyx/Doxil and pipeline plans)

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