The global market for human vaccines has experienced strong growth through 2008 and this is expected to continue through the forecast period. Growth will be fueled by new product introductions and rising usage in all regions.

This report, Vaccines 2009: Key Players, and Critical Trends in a Fast-Changing Industry), examines the market for vaccines used in humans to previous various types of disease. Sales estimates for each market segment represent global revenues and are expressed in current dollars. Estimates are provided for the historic 2008 period and forecasts are provided through 2013.

Since the last edition of this report:

• Vaccine makers are now advertising directly to the public with growing DTC budgets. The report identifies the possible market impact of this new trend.

• The economy has impacted vaccine sales with more people unable to make required out of pocket payments for vaccination.

• New categories of vaccines, such as allergy vaccines, are becoming more prominent, and have been included in our forecasts.

• Several major new products, including Wyeth's Prevnar 13, are on the horizon. The market impact of new products is discussed.

• Two major mergers - Pfizer/Wyeth and Merck/Schering-Plough, will impact the industry and this is considered in our market analysis.

Few areas of pharmaceuticals have seen the fast-moving developments in the marketplace that the vaccine market has in 2008. Since Kalorama Information last updated Kalorama Information's The World Market for Vaccines last year, new products and better than expected profits have transformed the vaccine marketplace. Continued sales of influenza vaccines and cervical cancer vaccines have provided a foundation for growth in the adult market. The competitive dynamics have changed with mergers, and many new products are on the way.

Kalorama Information's exhaustive research and analysis built from interviews with key decision makers in the market includes the following:

• Review of Products in the Market
• Current World Market Size for Pediatric and Adult Vaccines
• Segmented Revenues and Forecasts to 2013 by Category
• Over 45 Charts and Tables To Make Information Accessible
• Discussion of The Current Economy and Vaccines, Immunization Refusal, Swine/Avian Flu and Other Pandemics, Delivery Sys and other Trends in the Vaccine Market
• Important Vaccines and Immunization Schedules and Statistics
• Profiles of 15 Key Vaccine Companies
• Thorough Review of the Vaccine Pipeline and Possible Impact of New Products

Who are the main players in the vaccine market? What opportunities are available for pharmaceutical companies or investors from this market? What are the potential challenges vaccine competitors must deal with? What will be the impact of the first successful cancer product? What is the significance of at least one major acquisition to affect this industry? These questions and more are tackled in this report.

Current revenues and revenue forecasts to 2013 are included for the following pediatric vaccine categories:

• DTaP & DTP Vaccines
• Hep Vaccines
• HiB Vaccines
• MMR Vaccines
• Combination Vaccines
• Pneumococcal Vaccines
• Polio Vaccines
• Varicella Vaccines
• Other Pediatric Vaccines

As well as Revenues and Forecasts to 2012 for the following adult vaccine categories:

• Influenza Vaccines
• Hepatitis Vaccines
• Pneumococcal Vaccines
• Travel, DT and other Adult Vaccines
• Cervical Cancer

This is a rapidly changing marketplace and knowledge of the R&D pipeline is essential to truly understand what is happening in vaccines. Vaccines in development are discussed in this report, including vaccines for the following conditions:

• Enterotoxigenic Escherichia coli
• Parainfluenza Virus Type 3
• Pneumococcal Vaccines
• Respiratory Syncytial Virus<
• Cancers
• Cholera
• HIV/AIDS
• Helicobacter Pylori
• Malaria
• Rabies
• Tuberculosis
• West Nile Virus

This Kalorama Information report was created with a primary research effort. Historical information for this report was gathered from a wide variety of published sources including company reports and filings, government documents, legal filings, trade journals, newspapers and business press, analysts’ reports and other sources. Interviews with company representatives and other experts were conducted to capture the perspectives from industry participants’ point of view and assess trends, and form the basis of the forecasting and competitive analysis.

Additional Information

New York, October 29, 2009 - Highly publicized vaccine products not only boost the bottom lines of pharmaceutical companies, but also benefit insurance companies, doctors and retailers with their businesses, according to analysis of the recent flu vaccine season by life science market research publisher Kalorama Information. Kalorama estimates there is a multi-billion dollar market from ancillary products sold as a result of vaccines - from office visit copays, retail clinic fees, and indirect shopping revenue. None of these dollars are earned by drug giants, and the market is in addition to the intangible public relations benefits that many healthcare organizations realized from flu shots this year.

“Among the reasons vaccines are a popular play now in Pharma is that makers can count on many partners in the distribution process,” said Bruce Carlson, publisher of Kalorama Information. “The flu vaccine had demonstrated that retailers, providers and insurance companies all have incentives to piggyback off of the focus on vaccine products, and we expect that to be the same with new products.”

While attention is focused on the revenues that large drug makers such as GlaxoSmithKline, Novartis and Sanofi-Aventis may earn directly from selling their H1N1 vaccines, Kalorama estimates that there was an ancillary services and products market of nearly $5 billion in the U.S. from this year’s seasonal flu vaccine—likely more than any firm will earn from the products themselves. These revenues could be seen once again if H1N1 vaccines meet demand and are received as well as makers indicate they will be, based on early orders.

Ancillary revenues are earned by retail drugstore chains in the form of flu clinic fees, as well as purchases from customers visiting the store for the flu shot. Walgreen’s, the nation’s largest drugstore chain, administered 2.5 million seasonal flu shots by the end of September, according to the company in other media outlets. Rite Aid, CVS, Kroger, Target Pharmacy and other chains also held flu clinics. Kalorama estimates that drug chains earned at least $200 million from direct fees, but also an estimated $250 million in indirect revenues in the form of purchases by customers who came to the store to obtain a shot and would not have visited otherwise. In this particular analysis, Kalorama did not include products such as syringes or needle-free injectors, which are known to be selling briskly this season, and instead concentrated on distribution-related service revenues.

Kalorama’s conservative estimate of an ancillary services and products market assumes that most U.S. physicians saw at least one extra patient visit due to the vaccine availability. While most doctors depend on copay revenue to finance office operations, Kalorama notes that this does not mean doctors are profiting handsomely from vaccine copays.

“Doctor visits were down as a result of the recession, according to several surveys, and in general Americans do not follow the most advisable schedule of doctor visits, so if anything it is making up for unrealized revenue,” said Carlson. “It’s fair to say that anything that gets a patient into a doctor’s office - where there could be consultation about weight, blood sugar or other issues - can be viewed as a good thing.”

In addition to these ancillary revenues, a publicized health event such as the H1N1 vaccine offers an opportunity for insurance companies to develop an improved image. Wellpoint, Anthem Blue Health and many Blue Cross Blue Shield organizations nationwide are waiving copays for their insured members who receive the H1N1 vaccine. According to Kalorama, while waiving copays does not bring cash in the door, it does allow a major insurance company to build its image with its employer customers and also with the end-users at those companies in a way that would take a lot of advertising to accomplish.

Kalorama Information’s Vaccines 2009: World Market Analysis, Key Players, and Critical Trends in a Fast-Changing Industry contains estimates, forecasts and competitive analysis of the vaccine market.

About Kalorama Information
Kalorama Information supplies the latest in independent market research in the life sciences, as well as a full range of custom research services.

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