Chapter One: Introduction to Polymers for Medical Applications
Some Fundamental Concepts
Properties of Polymers
Physical Properties of Solid Polymers
Classes of Polymers Used in Medicine
Medical Polymers Come of Age
Legislation can Reduce the Risks of Innovation
Merging Polymer Science and Biology
Exciting Research: Biopolymer Optics and Electronics
Synthesizing Active Polymers with Potential Bio-Interfaces
Chapter Two: Biodegradable Polymers and Medical Applications
Medical Applications of Biodegradable Polymers
Currently Available Degradable Polymers
Chapter Three: Bone and Cartilage Replacement
Bone Morphogenic Proteins
Starting the Bone Growth Process
Tissue Engineers Build New Bone
New Stem Cell Sources
Artery/Cartilage Replacement Biomaterial
Production of Human-Like Finger Joint
Protein Delivery System May Help Fight Osteoporosis
Inorganic Materials and Enzymes Disperse into Biodegradable Composites
Cell-Loaded Matrix Can Repair Bones
Chapter Four: Dressings for Burns and Chronic Wounds
Chapter Five: Molecular Imprinted Polymers
Making an Imprint
Advantages and Limitations
Examples of Molecular Imprinted Polymers
Pros and Cons
Plastics with Molecular Memory
Molecular Imprinted Polymers for Chromatographic Separation
Preparation and Optimization
Cutting Edge Research and the Future
Chapter Six: Polymer Coatings and Surfaces for Medical Applications
Polymer Coatings for Medical Products
Polymer Coatings and Substrates for Drug Delivery Applications
Coating Process May Prevent Body from Rejecting Medical Implants
Surfaces Provide Key to Design of Clinically Useful Materials
Chapter Seven: Tissue Engineering
An Emerging Industry
Factors Driving Tissue Engineering Development
Dog Bladders and Human Hearts
Mass-Producing Polymer Scaffolds
Cell Culture in Three Dimensions
Preserving and Shipping Artificial Tissues and Organs
Chapter Eight: Product Development, Approval, and Regulations
Historical Overview of Medical Materials and Device Regulation
The Review and Approval Processes: Step by Step
Factors in Biocompatibility Evaluations
Who Writes Standards?
Who Uses Standards?
The American Society For Testing and Materials System
Chapter Nine: Market Perspective
The Healthcare Marketplace
The Evolution of Medical Polymers
Tissue Engineering: Spare Parts
Medical Coatings Market Segment
Diagnostic Testing Segment
Barriers to Progress
Chapter Ten: Company Profiles
Alexion Pharmaceuticals, Inc.
Alza Corporation (Johnson & Johnson)
Apogent Technologies Inc.
Arrow International, Inc.
Ballard Medical Products (Kimberly-Clark Health Care)
C. R. Bard, Inc.
Bausch & Lomb Inc.
Baxter International Inc.
Becton, Dickinson and Co.
Biocompatibles International Plc
Bionx Implants, Inc.
Boston Scientific Corporation
Carrington Laboratories, Inc.
Ciba Specialty Chemicals Holding Inc.
Clontech Laboratories, Inc.
Curative Health Services, Inc.
Imagyn Medical Technologies, Inc.
Imperial Chemical Industries Plc
Implant Sciences Corporation
Integra LifeSciences Holdings Corporation
Interpore International, Inc.
Medtronic Sofamor Danek, Inc.
Nobel Biocare AB
Ortec International, Inc.
Orthofix International N.V.
Planet Polymer Technologies, Inc.
Polymer Group, Inc.
Protein Polymer Technologies, Inc.
Smith & Nephew Plc
Sulzer Medica Ltd
Tutogen Medical Inc.
Wright Medical Group, Inc.
Zimmer Holdings, Inc.
Appendix A: Standard Terminology for Abbreviated Terms Relating to Plastics ASTM D 1600-92
Appendix B: Plaspec Materials Selection Database
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