U.S. Markets in Analytical Chip Technology: Gene, Protein, Tissue, Cell, and Microbiological Microarrays

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Published Mar 1, 2003 | 410 Pages | Pub ID: KLI803309

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The world of analytical microchips is the fastest growing technology segment in the life sciences today. The range of applications to which these miniature laboratories may be directed is very broad--covering fields as different as pharmaceutical development, food testing, clinical diagnostics, forensics, and environmental analysis. Moreover, while the number of such products is currently limited, the number of applications is rapidly expanding through the development of significant enabling technologies. Where chips were initially envisioned as carriers of microscopic binding sites for reactive molecules, today these chips are taking shape as miniature analyzers--smaller versions of analytical instrumentation. Newer chip technologies include microelectrophoresis and gas chromatography systems.

U.S. Markets in Analytical Chip Technology reports on the range of technologies currently available and in development, including DNA and protein chip technologies, tissue arrays, cellular arrays, reactive microchips, and more. In addition to the technologies and products in development, the report analyzes emerging applications and their market potential, including genomics, pharmacogenomics, drug discovery, proteomics, diagnostics, genetic family planning, prenatal testing, tissue-typing, agricultural and environmental applications, and food processing applications.

Extensive profiles of the industry’s top 20 participants, product reviews and R&D directions, as well as strategic planning and alliances are also included.

Chapter One: Executive Summary

    Scope and Methodology
    Size and Growth of Market

    • DNA/Gene Microarrays
    • Protein Microarrays
    • Microbiology Microarrays
    • Tissue Microarrays
    • Cell Microarrays

Chapter Two: Introduction

  • History and Development
  • Products

Chapter Three: DNA/Gene Microarrays


DNA/Gene Microarray Production

DNA/Gene Microarray Applications

  • Genotyping
  • Gene Expression Measurement
  • DNA/Gene Microassay Informatics

DNA/Gene Microarray Commercialization

  • Accelr8 Technology
  • Affymetrix
  • Agilent Technologies
  • Beckman Coulter
  • BioDiscovery
  • BioRobotics
  • Cartesian Technologies
  • Clontech
  • Display Systems Biotech
  • Exiqon
  • GeneMachines
  • Genomic Solutions
  • GSI Lumonics
  • Illumina
  • Imaging Research
  • Incyte Pharmaceuticals
  • Mergen Ltd.
  • Microarrays, Inc.
  • Operon Technologies
  • OriGene Technologies
  • PerkinElmer Life Sciences/NEN Division
  • PerkinElmer Life Sciences/Packard Instrument Division
  • ProtoGene Laboratories
  • R&D Systems
  • Research Genetics
  • Rosetta Inpharmatics
  • Schleicher and Schuell
  • Sequenom
  • Sigma-Genosys
  • Stratagene
  • TeleChem International
  • Vysis

Chapter Four: Protein Microarrays


Protein Array Technology

Protein Array Applications

  • Proteomics Solutions
  • Drug Discovery and Development
  • Clinical Diagnostics

Protein Microarray Commercialization

  • Advanced Array Technology
  • Aspira Biosystems, Inc.
  • Biacore AB
  • Biocept, Inc.
  • Ciphergen Biosystems, Inc.
  • Genicon Sciences Corporation
  • Genometrix
  • Hypromatrix, Inc.
  • MetriGenix, Inc.
  • Molecular Staging Inc.
  • Panomics, Inc.
  • PerkinElmer Life Sciences
  • PerkinElmer Life Sciences/Packard Bioscience
  • Prolinx, Inc.
  • Schleicher & Schuell BioSciences (S&S)
  • SomaLogic Inc.
  • Spinelix SA
  • TeleChem International

Chapter Five: Cell Microarrays


Cell Microarray Technology

Microarray Applications

  • Drug Discovery and Development
  • Toxicology

Cell Microarray Commercialization

Chapter Six: Tissue Microarrays


    Tissue Microarray Technology

    Tissue Microarray Applications

    • Johns Hopkins University
    • Ontario Cancer Institute/Princess Margaret Hospital
    • University of Basel (Switzerland)
    • University of Michigan Medical School
    • Leeds Medical School (United Kingdom)

    Tissue Microarray Commercialization

    • Ambion
    • Ardais
    • BD Biosciences/Pharmingen
    • Beecher Instruments
    • BioCat
    • BioGenex
    • Clinomics
    • Gentaur
    • Invitrogen
    • Molecular Histology
    • Phargentech Ltd.
    • SuperBioChips Laboratories

Chapter Seven: Microbiology Microarrays


Microbiology Array Technology

Microbiology Microarray Applications

  • Drug/Vaccine Discovery and Development
  • Pathogen Identification/Classification/Diagnosis

Microbiology Microarray Commercialization

  • Affymetrix
  • Ambion
  • Eurogenic
  • Nanogen
  • Qiagen
  • SigmaGenosys

Chapter Eight: Company Profiles

  • Accelr8 Technology Corporation
  • Affymetrix, Inc.
  • Agilent Technologies, Inc.
  • Akceli, Inc.
  • Alpha Innotech Corporation
  • Ambion, Inc.
  • Beecher Instruments, Inc.
  • BioDiscovery
  • Bio-Rad Laboratories
  • Ciphergen Biosystems Inc.
  • Gene Machines
  • MicroSurfaces, Inc.
  • Molecular Histology, Inc.
  • MWG Biotech, Inc. USA
  • Nanogen, Inc.
  • Orchid Biosciences, Inc.
  • PerkinElmer Life Sciences
  • Research Genetics/Invitrogen Corporation
  • Scanalytics, Inc.
  • TeleChem International

Chapter Nine: Market Analysis

  • Overview
  • DNA/Gene Microarrays
  • Protein Microarrays
  • Cell Microarrays
  • Tissue Microarrays
  • Microbiology Microarrays

Chapter Ten: Conclusions and Strategic Implications

  • First Conclusion
  • Second Conclusion
  • Third Conclusion
  • Fourth Conclusion
  • Fifth Conclusion
  • Sixth Conclusion
  • Seventh Conclusion

Appendix A: Glossary

Appendix B: Company Directory

List of Exhibits

  • Figure 1-1: The Total Market for Analytical Microarrays in the United States 2000-2010
  • Table 1-1: Estimated Market Sizes for the Top Five Applications Segments for Analytic Chips in the United States 2000-2010
  • Figure 1-2: Growth in the U.S. Market for DNA/Gene Microarray Products
  • Figure 1-3: Growth in the U.S. Market for Protein Microarray Products
  • Figure 1-4: Growth in the U.S. Market for Microbiological Microarray Products
  • Figure 1-5: Growth in the U.S. Market for Tissue Microarray Products
  • Figure 1-6: Growth in the U.S. Market for Cell Microarray Products
  • Table 2-1: Key Analytical Microchip Systems and Related Products
  • Table 2-2: Key Analytical Microarray Services
  • Table 2-3: Key Analytical Microchip Reagent Products
  • Table 2-4: Key Analytical Microchip Control Reagent Products
  • Table 2-5: Key Analytical Microchip Nucleic Acid Modifying Products
  • Table 2-6: Key Analytical Microchip Probe Labeling and Hybridization Products
  • Table 2-7: Key Analytical Microchip RNA Amplification Products
  • Table 2-8: Key Analytical Microchip Microscopy Products
  • Table 2-9: Key Analytical Microchip Imaging System Products
  • Table 2-10: Key Analytical Microchip Microarray Production Equipment and Supplies
  • Table 2-11: Key Analytical Microchip Microarray Scanners and Accessories
  • Table 3-1: Selected Genomics Databases
  • Table 4-1: Key Participants in Protein Microarray Technology
  • Table 6-1: Key Tissue Microarray Products
  • Table 7-1: Applications of Microarray Technology to Microbiological Research
  • Table 7-2: Key Microbiological Microarray Products
  • Table 9-1: Historic and Projected U.S. Markets for Analytical Microarrays: 2000-2010
  • Figure 9-1: Trends in the Historic and Projected U.S. Markets for Analytical Microarrays: 2000-2010
  • Table 9-2: Principal Competitors in DNA/Gene Microarray Technology
  • Table 9-3: Historic and Projected U.S. Markets for DNA/Gene Microarrays: 2000-2010
  • Figure 9-2: Trends in the Historic and Projected U.S. Markets for DNA/Gene Microarrays 2000-2010
  • Table 9-4: Historic and Projected U.S. Markets for Protein Microarrays: 2000-2010
  • Figure 9-3: Trends in the Historic and Projected U.S. Markets for Protein Microarrays 2000-2010
  • Table 9-5: Key Participants in the U.S. Protein Microarray Products Markets
  • Table 9-6: Historic and Projected U.S. Markets for Cell Microarrays 2000-2010
  • Figure 9-4: Trends in the Historic and Projected U.S. Markets for Cell Microarrays 2000-2010
  • Table 9-7: Historic and Projected U.S. Markets for Tissue Microarrays 2000-2010
  • Figure 9-5: Trends in the Historic and Projected U.S. Markets for Tissue Microarrays: 2000-2010
  • Table 9-8: Key Participants in Tissue Microarray Manufacturing and Marketing
  • Table 9-9: Historic and Projected U.S. Markets for Microbiology Microarrays 2000-2010
  • Figure 9-6: Trends in the Historic and Projected U.S. Markets for Microbiology Microarrays 2000-2010