Cardiac Markers

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Published Jun 16, 2016 | 71 Pages | Pub ID: KLI15030206

Cardiac Markers

Biomarkers are biological or biochemical molecules, or genetic changes, or other characteristics that can be measured, and that indicate or predict a condition, risk, or likely response. Biomarkers can be used for a range of diagnostic applications including predicting disease risk, diagnosis, predicting prognosis, identifying appropriate therapy for an individual, monitoring disease or for return of a disease, and other applications. With the incidence of cardiovascular disease increasing greatly, cardiac markers and cardiovascular biomarkers are in huge demand. Cardiac Markers provides market assessment, estimate and competitive analysis for tests for cardiovascular disease (CVD) that use biomarkers, including:
  • Worldwide Cardiovascular Disease Biomarkers Diagnostic Market – 2015 and 2020
  • Selected IVD Markers of Cardiovascular Disease
  • Selected Biomarkers and Biomarker Panels for Cardiovascular Disease, and Companies Developing/Marketing These Biomarkers
  • Selected Lipid Biomarkers, and Companies Developing/Marketing These Biomarkers
Physicians use cardiac markers (CK-MB, troponin I, troponin T, myoglobin, brain natriuretic peptide (BNP), proBNP, high sensitive C-reactive protein (hsCRP), and homocysteine) and cardiovascular biomarkers in two ways: acute care to diagnose a cardiac event in a hospital emergency room (acute care) or chronic care to evaluate the risk of a cardiovascular event occurring and to monitor patients with a cardiovascular disease. The traditional markers — CK-MB, troponin and myoglobin – were used in acute care and tests such as cholesterol were used to evaluate risk.

In the past few years cardiac markers have been revitalized with tests such as myeloperoxidase (MPO) brain natriuretic peptide (BNP), proBNP becoming part of the acute care test menu and tests such as high sensitive C-reactive protein (hsCRP), high sensitive troponin, homocysteine, Fatty Acid Binding Protein (FABP), Glycogen Phosphorylase isoenzyme BB (GPBB), urinary albumin, S-100 protein and hemoglobin A1c (hbA1c) now part of the risk evaluation tool box.

Cardiac Markers reviews the progression of cardiac diagnostic technologies and notes some trends in test strategies as well, including:
  • Cardiac Risk
  • Genetics and Cardiovascular Disease
  • Acute Myocardial Infarction and Acute Coronary Syndrome
  • Heart Failure
  • Lipid Disorders
  • ACP Coronary Heart Disease Screening
As diagnostic companies strive to provide platforms allowing for quick yet accurate diagnoses of patients, there is growing opportunity in the cardiac marker market. In the U.S., the Affordable Care Act (ACA), which is designed to advance healthcare accessibility, has helped to drive the market. The ACA encourages a shift toward payment based on the value of care.

There are currently a number of companies developing or marketing cardiac markers and cardiovascular biomarkers. This report contains profiles of many of the top competitors, including:
  • Abbott Laboratories
  • American Laboratory Products Company (ALPCO)
  • ARUP Laboratories
  • Axis-Shield Diagnostics, Ltd. (An Alere Company)
  • Beckman Coulter, Inc. (Subsidiary of Danaher Corporation)
  • bioMérieux SA
  • CardioDx, Inc.
  • CardioGenics Holdings, Inc.
  • Diagenics International Corporation
  • Gamma Therapeutics, Inc.
  • Quest Diagnostics
  • Ortho-Clinical Diagnostics
  • Randox Laboratories Ltd.
  • Roche Diagnostics
  • Siemens Healthcare Diagnostics
  • Tosoh Corporation / Tosoh Bioscience, Inc.
The information presented in this report is derived on publicly available information sources such as company, government, and medical organization reports. The analysis is based on the author's industry knowledge combined with literature searches and interviews with industry professionals and experts in the areas of in vitro diagnostics and personalized medicine.
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