Healthcare Turns to Mass Spectrometry to Combat Infectious Disease

Healthcare Turns to Mass Spectrometry to Combat Infectious Disease

The concept of breaking down compounds, charging or ionizing them, in order to determine their properties, or mass spectrometry, is a technology first developed several decades ago and cofinded deep in research laboratories. Now it’s becoming as important a testing tool and other in vitro diagnostic analyzers. New improvements in the old technology such as laser desorption and electrospray have made these machines usable for protein and DNA work, and innovative companies have put them to work combating disease threats such as cancer and infectious disease.


Microbiology Diagnostics Is Alive and Well - Beckman Coulter Adds to its Core Testing Solutions

Microbiology Diagnostics Is Alive and Well - Beckman Coulter Adds to its Core Testing Solutions

The following analysis is derived from Kalorama Information’s upcoming report on the global infectious disease test market. The report’s prior edition, The Worldwide Market for Infectious Disease Diagnostic Tests , is also available.

This post discusses the potentially undervalued move by Beckman Coulter to enter the market for traditional microbiology diagnostics or ID/AST systems at a time when many mid-sized and major IVD companies have focused on molecular diagnostic methods. Similarly aus...


The New Workhorses in Proteomics Research - Q-TOFs and Orbitraps

The New Workhorses in Proteomics Research - Q-TOFs and Orbitraps

Changes in the competitive and technological landscape of proteomics research can take a long time to take hold. Core instruments in translational research for biomarkers and drug targets, such as mass spectrometers (MS), may be replaced or upgraded in a laboratory only once every ten to fifteen years. Many proteomics core labs at universities and research centers still rely on manufacturer-discontinued MS systems, though reinforcements in the lab have been conspicuous in recent years. New MS te...


Mass Spec Imaging Develops Tissue Samples as Resource for Proteomic Biomarker Discovery

This blog post covers market trends in proteomics research - a field recently profiled by Kalorama Information with Proteomics Research Markets: Instruments (Mass Spectrometry, Liquid Chromatography, Electrophoresis), Disease Areas (Oncology, Cardio/Blood, Neurology, Other) Market Share and Trends. The report offers unique insight into a mass spectrometry- and analytical separation-centric life sciences market, including market shares by geography, instrument type, and vendor.

Mass spectrometr...


Case Studies in Clinical Mass Spectrometry: An “Electronic Nose”

Case Studies in Clinical Mass Spectrometry: An “Electronic Nose”

Kalorama Information has profiled the unique and growing contributions of mass spectrometry technology to clinical in vitro diagnostics , and the pace of discovery in the field continues to impress. Researchers at the University of Leicester have developed an “electronic nose” capable of rapidly characterizing Clostridium difficile strains in infected patients. While the MALDI TOF form of mass spectrometry has been useful in identifying pathogens by cell surface proteins, the mass spec “electron...


Ionizing Tea Leaves - Kalorama Explores the Future of Clinical Mass Spectometry

Ionizing Tea Leaves - Kalorama Explores the Future of Clinical Mass Spectometry

The sophistication and analytical flexibility of mass spectrometry systems traditionally excluded them from routine clinical diagnostics. Today, mass spectrometry and its derivative technologies - gas chromatography mass spectrometry (GC-MS), liquid chromatography mass spectrometry (LC-MS), liquid chromatography tandem mass spectrometry (LC-MS/MS), and others - are seeing increasingly wider usage in healthcare. Led by the rising application of matrix-assisted laser desorption/ionization time-of-...