Downstream Bioprocessing Markets (Chromatography Columns and Resins, Membrane Adsorbers, Filtration Systems, Sensors)

 
   Single User - $4,500
   Site License (one location, 10 users) - $6,750
   Corporate License - $9,000


Loading...
Published Oct 2, 2018 | 171 Pages | Pub ID: KLI15784298

Downstream Bioprocessing Markets (Chromatography Columns and Resins, Membrane Adsorbers, Filtration Systems, Sensors)

Bioprocessing consists of two major processing steps: upstream and downstream processing. Upstream processing refers to the culturing of cells and microorganisms to create biologically active product for use in research and in the production of biopharmaceuticals. This processing is typically done through cell culture or fermentation. Downstream processing refers to the separation and refinement of bulk bioproduct into a form suitable for its end use. Typically, this processing includes separation, purification and sterilization. Downstream Bioprocessing Markets analyzes the current and potential world market for downstream bioprocessing and includes the following global market data for downstream bioprocessing components:
  • World Downstream Bioprocessing Markets, 2016-2021 ($ billions)
  • World Downstream Bioprocessing Markets by Geography, 2016-2021 ($ billions) (US, Western Europe, Eastern Europe, APAC [China, Japan, S. Korea, India, Others], Latin America, ROW)
  • World Downstream Bioprocessing Markets by Geography, 2017 (%) (US, Western EU, Eastern EU, APAC, ROW, SA)
  • Downstream Components Bioprocessing Market Share by Vendor 2018 (%)
Chromatography Columns and Resins

The chromatography columns and resins segment of the downstream bioprocessing components market is a large segment. There are many issues driving this segment. The continuous need for new and different column and resin technologies continues to drive growth of this market segment as bioprocessors battle what they say is their biggest downstream bottleneck. The report includes the following global market data for downstream bioprocessing chromatography columns and resins markets:
  • World Downstream Bioprocessing Chromatography Columns and Resins Markets, 2016-2021 ($ billions)
  • World Downstream Bioprocessing Chromatography Columns and Resins Markets by Geography, 2016-2021 ($ billions) (US, Western Europe, Eastern Europe, APAC [China, Japan, S. Korea, India, Others], Latin America, ROW)
  • World Downstream Bioprocessing Chromatography Columns and Resins Markets by Geography, 2017 (%) (US, Western EU, Eastern EU, APAC, ROW, SA)
Membrane Adsorbers

Membrane adsorbers are thin, synthetic, porous membranes modified with functional groups similar to those on equivalent resins. Membrane adsorbers are growing in use, finding more deployment in flexible manufacturing facilities in which speed of operations and robust performance are essential production criteria. The report includes the following global market data for downstream bioprocessing membrane adsorber markets:
  • World Downstream Bioprocessing Membrane Adsorber Market, 2016-2021 ($ millions)
  • World Downstream Bioprocessing Membrane Adsorber Market by Geography, 2016-2021 ($ millions) (US, Western Europe, Eastern Europe, APAC [China, Japan, S. Korea, India, Others], Latin America, ROW)
  • World Downstream Bioprocessing Membrane Adsorber Market by Geography, 2017 (%) (US, Western EU, Eastern EU, APAC, ROW, SA)
Filtration Systems

The filtration segment of the downstream bioprocessing market includes microfiltration, ultrafiltration, nanofiltration, reverse osmosis, and ion-exchange filtration. Filtration is important for harvesting biologic actives from cell media and other downstream separations because biomolecules are highly sensitive to heat and chemicals. The segment is being spurred by the general increase in biodrug products. Downstream Bioprocessing Markets includes the following global market data for downstream bioprocessing filtration markets:
  • World Downstream Bioprocessing Filtration Market, 2016-2021 ($ billions)
  • World Downstream Bioprocessing Filtration Market by Geography, 2016-2021 ($ billions) (US, Western Europe, Eastern Europe, APAC [China, Japan, S. Korea, India, Others], Latin America, ROW)
  • World Downstream Bioprocessing Filtration Market by Geography, 2017 (%) (US, Western EU, Eastern EU, APAC, ROW, SA)
Sensors

In a fast-paced production environment, in which the various processing steps must be closely monitored, bioprocessors must implement advanced control technologies. Many are applying novel automation and software systems to monitor and control bioprocessing. On-line technologies that can monitor, control, and improve downstream process steps significantly benefit bioprocessors. They can optimize the quality of their product by harnessing the timely data on critical operational and quality parameters available by implementing on-line monitoring systems, such as sensors. Sensor technology can help the industry better manage key challenges, such as having to comply with new regulations, and address cost control and risk issues during drug development and production. The report includes the following global market data for downstream bioprocessing sensor markets:
  • World Downstream Bioprocessing Sensor Market, 2016-2021 ($ billions)
  • World Downstream Bioprocessing Sensor Market by Geography, 2016-2021 ($ billions) (US, Western Europe, Eastern Europe, APAC [China, Japan, S. Korea, India, Others], Latin America, ROW)
  • World Downstream Bioprocessing Sensor Market by Geography, 2017 (%) (US, Western EU, Eastern EU, APAC, ROW, SA)
Market Trends and Drivers, Challenges, and Developments

Even though bioprocessors and others in the industry have been in business for a number of years, they face a number of issues and challenges to their continued success and the development of future therapeutics. Advances in science and technology, as well as new demands from customers, present a continuous flow of issues to be addressed. Bioprocessors must innovate to be able to continue to command premium prices. For them, speed, process innovation, and operational excellence are must-win battles. Market trends and drivers, challenges, and developments are discussed in the report.

The Market Landscape

The report notes that advances in technology and bioprocessing equipment are making it possible to develop quality biologic drugs. This is increasing the use of bioprocessing equipment, which drives the biopharmaceutical market. The growing numbers of elderly, notably those suffering from chronic illnesses, will help generate a continuing need for novel biotherapeutic drugs. And as demand increases, bioprocessors will need processing technologies and components that will facilitate the production of high quality products. As a result, the significance of the downstream bioprocessing market will grow.

Competitive Analysis

The report contains profiles of a wide range of companies. The downstream bioprocessing market players profiled in the report include:
  • 3M Company
  • Abec
  • Alfa Laval
  • Avantor Performance Materials
  • BIA Separations
  • Boehringer Ingelheim Pharmaceuticals
  • Bosch
  • Dow
  • ESI Ultrapure
  • Finesse Solutions
  • FujiFilm Diosynth biotechnologies
  • GE Healthcare Life Sciences
  • GEA Germany Düsseldorf
  • Lonza Group
  • MilliporeSigma
  • Natrix Separations
  • Nordson Medical
  • Pall Biotech
  • Parker Hannifin
  • Repligen
  • Sartorius AG
  • Thermo Fisher Scientific
  • W. L. Gore & Associates, Inc.
  • Watson-Marlow Fluid Technology Group
Market forecasts cover various segments and are based on an examination of current market conditions and on investigations into the development of new products by key companies. The market data provide multiple year forecasts for different product segments covered in the report. The information presented in this report is the result of data gathered from company product literature and other corporate brochures and documents, as well as information found in the scientific and trade press. In addition, interviews were conducted with company executives.
  • Executive Summary
    • Overview
      • Focus on Cost Effectiveness
      • Outsourcing Popular
      • Flexibility and More Research Needed
        • Table World Market for Downstream Bioprocessing Components, 2016-2021 ($ billions)
    • Methodology
  • Introduction
    • Downstream Processing
      • Table The State of Downstream Bioprocessing
      • Important Roles
        • Table Key Roles of Downstream Bioprocessing
      • Safety and Efficacy
    • Stages of Downstream Processing
      • Table Stages of Downstream Bioprocessing
      • Solid-Liquid Separation
      • Intracellular Product Release
      • Product Concentration
      • Chromatography Purification
      • Formulation
    • Changes in Production Nature
      • Table Current Biopharmaceutical Product Mix
      • Innovation Required
      • Globalization Continues
    • The Need for Operational Excellence
    • Competition Generating Cost Efficiencies
      • Downstream Resistance
      • Process Intensification
      • Higher Titers
      • New Technologies
      • Flexibility
      • Integration and Automation
      • Continuous Processing
    • Developing Research Areas
      • Chromatography
      • Resins
      • Alternative Processes for Purification
      • Spectroscopy
    • Filtration Technologies Advance
      • Tangential Flow
      • Automated
      • Gel Filtration Chromatography
      • Precipitation Alternative
      • Slow Adoption of New Technologies
    • Outsourcing
      • Core Competencies
      • Drivers
      • Issues
      • The Future
  • Trends and Drivers
    • Table Key Trends in Downstream Bioprocessing
    • Protein A
    • Molecule Issues
    • Chromatography
      • Table Application of Single Use Technology Downstream (percentage of overall use)
    • Streamlining and Redesigning
      • Streamlining Niches
    • Purification
    • Greater Use of Contract Manufacturers
    • Production Efficiency
    • International
    • Cancer Therapy Push
    • Collaborations and Innovation
  • Challenges
    • Chromatography
    • Continuous Processing
    • Titers and Composition
    • Evolving Clarification and Purification Strategies
    • Capacity Bottlenecks
    • Isolation of Proteins
    • Efficiencies
    • Quality by Design
    • Talent Shortage
  • Market Developments
    • Collaboration to Improve Downstream Bioprocessing
    • Start-up Acquisition
    • Promoting Pre-Packed Columns
    • Next Generation Columns
    • Next Generation Affinity Ligands
    • Immunoglobulin Facility
    • Bioprocessing Services
    • Expansion
    • Acquisition
    • Supply Deal
    • Bioconjugation Process
    • New Structured Substrates
    • New Protein A Chromatography Resin
    • Enterprise Software Increases Throughput and Quality
    • Investing in Protein Expression Platform
  • Market Landscape
    • Overview
    • Drivers
      • Table Key Drivers of Downstream Bioprocessing
      • Expanding Therapies and Markets
    • Market Analysis and Forecasts
      • Biosimilars
      • Growth and Emerging Markets
      • Continuous Processing
    • Global Market for Downstream Bioprocessing Components
      • Table Downstream Components Bioprocessing Market Share by Vendor 2018 (%)
      • Table World Downstream Bioprocessing Markets, 2016-2021 ($ billions)
      • Table World Downstream Bioprocessing Markets by Geography, 2016-2021 ($ billions)
      • Table World Downstream Bioprocessing Markets by Geography, 2017 (%)
      • Chromatography Columns and Resins
        • Table World Downstream Bioprocessing Chromatography Columns and Resins Markets, 2016-2021 ($ billions)
        • Table World Downstream Bioprocessing Chromatography Columns and Resins Markets by Geography, 2016-2021 ($ billions)
        • Table World Downstream Bioprocessing Chromatography Columns and Resins Markets by Geography, 2017 (%)
      • Membrane Adsorbers
        • Table World Downstream Bioprocessing Membrane Adsorber Market, 2016-2021 ($ millions)
        • Table World Downstream Bioprocessing Membrane Adsorber Market by Geography, 2016-2021 ($ millions)
        • Table World Downstream Bioprocessing Membrane Adsorber Market by Geography, 2017 (%)
      • Filtration Systems
        • Table World Downstream Bioprocessing Filtration Market, 2016-2021 ($ billions)
        • Table World Downstream Bioprocessing Filtration Market by Geography, 2016-2021 ($ billions)
        • Table World Downstream Bioprocessing Filtration Market by Geography, 2017 (%)
      • Sensors
        • Table World Downstream Bioprocessing Sensor Market, 2016-2021 ($ billions)
        • Table World Downstream Bioprocessing Sensor Market by Geography, 2016-2021 ($ billions)
        • Table World Downstream Bioprocessing Sensor Market by Geography, 2017 (%)
  • Corporate Profiles
    • 3M Company, St. Paul, MN 55144, www.3m.com/3M/en_US/company-us
    • Abec, Bethlehem, PA 18017, www.abec.com
    • Alfa Laval, Lund, Sweden, www.alfalaval.com
    • Avantor Performance Materials, Center Valley, PA 18034, www.avantorinc.com
    • BIA Separations, Ajdovšèina, Slovenia, www.biaseparations.com
    • Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT 06877, www.bioxcellence.com
    • Bosch, Stuttgart, Germany, www.bosch.de/en/
    • Dow, Midland, MI, www.dow.com
    • ESI Ultrapure, Cwmbran, Torfaen, NP44 3XS, UK, www.esiultrapure.com
    • Finesse Solutions, Santa Clara, CA 95054, www.finesse.com
    • FujiFilm Diosynth biotechnologies, College Station, TX 77845, www.fujifilmdiosynth.com
    • GE Healthcare Life Sciences, Marlborough, MA 01752, https://www.gelifesciences.com/ solutions/bioprocessing/productsand- solutions/downstream-bioprocessing
    • GEA Germany Düsseldorf, 40468 Düsseldorf, Germany, www.gea.com/en
    • Lonza Group, Basel, Switzerland, www.lonza.com
    • Millipore, Millipore Sigma, Burlington, MA 01803, www.emdmillipore.com
    • Natrix Separations, Burlington, Ontario, L7L 6A8 Canada, www.natrixseparations.com
    • Nordson Medical, Marlborough, MA 01752, www.nordsonmedical.com
    • Pall Biotech, Port Washington, NY 11050, https://biotech.pall.com
    • Parker Hannifin, Cleveland, OH 44124, www.parker.com
    • Repligen, Waltham, MA 02453, www.repligen.com
    • Sartorius AG, Goettingen, Germany, www.sartorius.com
    • Thermo Fisher Scientific, Waltham, MA 02451, https://www.thermofisher.com/us/en/home/lifescience/ bioproduction.html
    • W. L. Gore & Associates, Inc., Newark, DE 19711, www.gore.com
    • Watson-Marlow Fluid Technology Group, Falmouth, TR11 4SZ UK, www.watson-marlow.com

In this report, {{keyword[keywordTextProperty]}} appears {{keyword[keywordCountProperty]}} times. {{searchResults.STATRESULT.SUMMARY.KW[keywordTextProperty]}} appears {{searchResults.STATRESULT.SUMMARY.KW[keywordCountProperty]}} times.

We were unable to search inside this report.
No results matched your search criteria.

Search for an exact word or phrase by placing the word or phrase in quotation marks ("market trend"). Search for different versions or tenses of a word by placing an asterisk at the end of the word (pharma*).

Please note that your term must be at least three characters long and numbers will be blocked by the # sign.