Single Use Upstream Bioprocessing Markets (Bioreactors, Media Bags, Bioprocess Containers, Tubing and Connectors, Mixing Systems, Sensors and Probes)

 
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Published May 4, 2018 | 174 Pages | Pub ID: KLI15676851

Single Use Upstream Bioprocessing Markets (Bioreactors, Media Bags, Bioprocess Containers, Tubing and Connectors, Mixing Systems, Sensors and Probes)

Bioprocessing consists of two major processing steps: upstream and downstream processing. Upstream processing refers to the culturing of cells and microorganisms to create biologically active product for use in research and in the production of biopharmaceuticals. This processing is typically done through cell culture or fermentation. Downstream processing refers to the separation and refinement of bulk bioproduct into a form suitable for its end use. Typically, this processing includes separation, purification and sterilization. Single Use Upstream Bioprocessing Markets (Bioreactors, Media Bags, Bioprocess Containers, Tubing and Connectors, Mixing Systems, Sensors and Probes) analyzes the current and potential world market for single use systems for upstream bioprocessing and includes the following market data:
  • World Market for Single Use Upstream Processing, 2016-2021 (Single Use Bioreactors, Single Use Media Bags, Single Use Bioprocess Containers, Single Use Tubing and Connectors, Single Use Mixing Systems, Single Use Pressure Sensors and Probes, Single Use Temperature Sensors and Probes, Single Use pH Sensors and Probes, Single Use Dissolved Oxygen Sensors and Probes, Single Use Other Probes and Sensors, World Totals)
  • World Market for Single Use Upstream Processing by Geography, 2016-2021 (US, Western Europe, Eastern Europe, APAC, Latin America, ROW)
  • Single Use Bioreactors
  • Single Use Bioreactor Market Share by Type of Molecule, 2018 (%)
  • World Market for Single Use Bioreactors, 2016-2021
  • World Market for Single Use Bioreactors by Geography, 2016-2021 (US, Western Europe, Eastern Europe, APAC, China, Japan, S. Korea, India, Others, Latin America, ROW)
Single Use Media Bags
  • World Market for Single Use Media Bags, 2016-2021
  • World Market for Single Use Media Bags by Geography, 2016-2021 (US, Western Europe, Eastern Europe, APAC, China, Japan, S. Korea, India, Others, Latin America, ROW)
  • Single Use Bioprocess Containers
  • World Market for Single Use Bioprocess Containers, 2016-2021
  • World Market for Single Use Bioprocess Containers by Geography, 2016-2021 (US, Western Europe, Eastern Europe, APAC, China, Japan, S. Korea, India, Others, Latin America, ROW)
Single Use Tubing and Connectors
  • World Market for Single Use Tubing and Connectors, 2016-2021
  • World Market for Single Use Tubing and Connectors by Geography, 2016-2021 (US, Western Europe, Eastern Europe, APAC, China, Japan, S. Korea, India, Others, Latin America, ROW)
  • Single Use Mixing Systems
  • World Market for Single Use Mixing Systems, 2016-2021
  • World Market for Single Use Mixing Systems by Geography, 2016-2021 (US, Western Europe, Eastern Europe, APAC, China, Japan, S. Korea, India, Others, Latin America, ROW)
Single Use Sensors and Probes
  • World Market for Single Use Sensors and Probes, 2016-2021
  • World Market for Single Use Sensors and Probes by Geography, 2016-2021 (US, Western Europe, Eastern Europe, APAC, China, Japan, S. Korea, India, Others, Latin America, ROW)
  • Single Use Pressure Sensors and Probes
  • World Market for Single Use Pressure Sensors and Probes, 2016-2021
  • World Market for Single Use Pressure Sensors and Probes by Geography, 2016-2021 (US, Western Europe, Eastern Europe, APAC, China, Japan, S. Korea, India, Others, Latin America, ROW)
Single Use Temperature Sensors and Probes
  • World Market for Single Use Temperature Sensors and Probes, 2016-2021
  • World Market for Single Use Temperature Sensors and Probes by Geography, 2016-2021 (US, Western Europe, Eastern Europe, APAC, China, Japan, S. Korea, India, Others, Latin America, ROW)
  • Single Use pH Sensors and Probes
  • World Market for Single Use pH Sensors and Probes, 2016-2021
  • World Market for Single Use pH Sensors and Probes by Geography, 2016-2021 (US, Western Europe, Eastern Europe, APAC, China, Japan, S. Korea, India, Others, Latin America, ROW)
Single Use Dissolved Oxygen Sensors and Probes
  • World Market for Single Use Dissolved Oxygen Sensors and Probes, 2016-2021
  • World Market for Single Use Dissolved Oxygen Sensors and Probes by Geography, 2016-2021 (US, Western Europe, Eastern Europe, APAC, China, Japan, S. Korea, India, Others, Latin America, ROW)
Single Use Upstream Bioprocessing Trends

This report generally reviews the nature and direction of research, as well as future markets. Trends in single use upstream bioprocessing trends are discussed, including:
  • Robust Expansion
  • Product Titer Growth
  • Perfusion
  • Retrofitting Facilities
  • Flexibility
  • Cell Retention and Capacity
  • Reducing Utility Costs
  • Modular Facilities
  • Local Production
Market Drivers

Single Use Upstream Bioprocessing Markets indicates some key drivers of single use bioprocessing technologies. A variety of issues have been spurring the overall growth of the single use bioreactors and systems market. These include a better potential return on investment for biopharmaceutical companies and contract manufacturing organizations; reduced complexity in automation; lower costs; and less of a need for validation and cleaning between processes. Also spurring on the market are the energy efficiency of single use bioreactors, and ease of cultivation of marine organisms, such as algae.Research and development departments of biopharmaceutical manufacturers, research institutes, and contract manufacturing organizations are among the major end users of single use systems, followed by biopharmaceutical manufacturers. The interest in the research segment can be attributed to the wide acceptance of single use bioreactors by small- and mid-scale biopharmaceutical manufacturing companies for clinical testing and research and development purposes.

Competitive Analysis

The report indicates single use bioprocessing market share (%) by vendor for 2018 and as well contains profiles of the following market participants:
  • Abec
  • Applikon Biotechnology
  • Broadley-James Corp.
  • Cellexus
  • Cellon SA
  • Celltainer Biotech BV
  • CerCell ApS
  • CPC (Colder Products Company)
  • Cronus-PCS
  • EireChrom
  • Eppendorf
  • ESI Ultrapure
  • Finesse Solutions
  • GE Healthcare’s Life Sciences Business
  • Hamilton Robotics
  • Holland Applied Technologies
  • Millipore, Millipore Sigma
  • NewAge Industries
  • Pall Biotech
  • Parker Hannifin
  • PBS Biotech
  • PendoTech
  • PerfuseCell A/S
  • PreSens Precision Sensing
  • ProlifeCell
  • PumpCell A/S
  • Refine Technology
  • Sartorius AG
  • Stobbe Tech
  • Sysbiotech
  • Thermo Fisher Scientific
  • Zeta Holding
Market forecasts cover various segments and are based on an examination of current market conditions and on investigations into the development of new products by key companies. The market data provide multiple year forecasts for different product segments covered in the report. The information presented in this report is the result of data gathered from company product literature and other corporate brochures and documents, as well as information found in the scientific and trade press. In addition, interviews were conducted with company executives.
  • Executive Summary
    • Overview
    • Methodology
    • Market Overview
      • Table World Market for Single Use Upstream Processing, 2016-2021 ($ millions)
      • Table World Market for Single Use Upstream Processing by Geography, 2016-2021 ($ millions)
  • Introduction
    • Upstream Bioprocessing Perspective
      • Bioreactors
      • Single Use Bioreactors
      • Other Single Use Products
    • Traditional Processing
    • Disposable Processing
      • Methodical Progress
      • Components and Regulation
      • Some Impediments
      • But Biosimilar and Biologics Opportunities
    • Variations in Bioreactor Types
      • Stainless Steel
      • Stirred-Tank Reactors
      • Airlift Fermenters
      • Packed Bed Reactors
      • Hollow-Fiber Reactors
      • Single Use Systems
        • Table Traditional and Single Use Bioreactor Features
    • Flexibility
      • Vaccine Manufacture
      • Product Variety
    • But Challenges Loom
      • Alternating Scales
      • Automation
      • Compliance
      • Distribution
      • Integrity
    • Yet Opportunities in Targeted Therapeutics
      • Newer Protein Therapies
      • Cell-Culture-Based Technology
      • Cost-Effective Solution
      • Outsourcing Continues
      • Capacity Investment Shifting
  • Single Use Bioprocessing Trends
    • Robust Expansion
    • Product Titer Growth
    • Perfusion
      • Intensified Perfusion
    • Retrofitting Facilities
    • Flexibility
    • Cell Retention and Capacity
    • Reducing Utility Costs
    • Modular Facilities
    • Local Production
  • Issues Facing Single Use Bioprocessing
    • Single Use or Stainless
    • Some Costs Involved
    • Vendor Auditing
    • Regulatory Challenges
      • Leaching
    • Qualifying Vendors
      • Plastic Purity
    • Customization
    • Standardization
  • Market Developments
    • 4,000 Liter Single-Use Bioreactor Installed
    • Disposable Mixing Systems
    • Smart Sensors
    • Non-GMP Pilot Plant
    • Continuous Bioprocess Laboratory
    • Disposable Technologies for Scale Up
    • Maximizing Efficiency - Customization
    • Single Use Storage Containers
    • Single Use Specialist
    • Driving Single Use
    • New Test Center
    • New Modular Facility System
    • Single Use for Cell Therapy
  • Market Landscape
    • Early Penetration
    • Niche Opportunities
    • Integral to Bioprocessing
    • Demand from Local Markets
    • Market Disruption
    • Beyond the Small Scale
    • Different Manufacturing Options Possible
    • Opportunities for Suppliers
    • Smaller Targeted Markets
      • Table Single Use Technology Utilization (%)
    • Markets in Transition
      • Diversity
      • Continuous Flow Processing
      • More Responsive Supply Chain
      • Drivers
        • Table Key Drivers of Single Use Systems
  • Market Analysis and Forecasts
    • Wide Acceptance Worldwide
      • Emerging Markets
    • Stainless Steel Still Competitive
      • Table Single Use Bioreactor Usage by Process 2018 (%)
      • Table Single Use Bioprocessing Market Share by Vendor 2018 (%)
    • Single Use Bioreactors
      • Table Single Use Bioreactor Market Share by Type of Molecule, 2018 (%)
      • Table World Market for Single Use Bioreactors, 2016-2021 ($ millions)
      • Table World Market for Single Use Bioreactors by Geography, 2016-2021 ($ millions)
    • Single Use Media Bags
      • Table World Market for Single Use Media Bags, 2016-2021 ($ millions)
      • Table World Market for Single Use Media Bags by Geography, 2016-2021 ($ millions)
    • Single Use Bioprocess Containers
      • Table World Market for Single Use Bioprocess Containers, 2016-2021 ($ millions)
      • Table World Market for Single Use Bioprocess Containers by Geography, 2016-2021 ($ millions)
    • Single Use Tubing and Connectors
      • Table World Market for Single Use Tubing and Connectors, 2016-2021 ($ millions)
      • Table World Market for Single Use Tubing and Connectors by Geography, 2016-2021 ($ millions)
    • Single Use Mixing Systems
      • Table World Market for Single Use Mixing Systems, 2016-2021 ($ millions)
      • Table World Market for Single Use Mixing Systems by Geography, 2016-2021 ($ millions)
    • Single Use Sensors and Probes
      • Table World Market for Single Use Sensors and Probes, 2016-2021 ($ millions)
      • Table World Market for Single Use Sensors and Probes by Geography, 2016-2021 ($ millions)
      • Single Use Pressure Sensors and Probes
        • Table World Market for Single Use Pressure Sensors and Probes, 2016-2021 ($ millions)
        • Table World Market for Single Use Pressure Sensors and Probes by Geography, 2016-2021 ($ millions)
      • Single Use Temperature Sensors and Probes
        • Table World Market for Single Use Temperature Sensors and Probes, 2016-2021 ($ millions)
        • Table World Market for Single Use Temperature Sensors and Probes by Geography, 2016-2021 ($ millions)
      • Single Use pH Sensors and Probes
        • Table World Market for Single Use pH Sensors and Probes, 2016-2021 ($ millions)
        • Table World Market for Single Use pH Sensors and Probes by Geography, 2016-2021 ($ millions)
      • Single Use Dissolved Oxygen Sensors and Probes
        • Table World Market for Single Use Dissolved Oxygen Sensors and Probes, 2016-2021 ($ millions)
        • Table World Market for Single Use Dissolved Oxygen Sensors and Probes by Geography, 2016-2021 ($ millions)
  • Corporate Profiles
    • Abec, Bethlehem, PA 18017, www.abec.com
    • Applikon Biotechnology, Delft, Netherlands, www.applikon-bio.com
    • Broadley-James Corp., Irvine, CA 92618, www.broadleyjames.com
    • Cellexus, Dundee, UK, www.cellexus.com
    • Cellon SA, Grand Duché du Luxembourg, www.cellon.lu
    • Celltainer Biotech BV, Winterswijk Brinkheurne, The Netherlands, www.celltainer.com
    • CerCell ApS, Holte Denmark, www.cercell.com
    • CPC (Colder Products Company), St. Paul, MN 55114, www.cpcworldwide.com
    • Cronus-PCS, DK-2840 Holte, Denmark, www.cronus-pcs.com
    • EireChrom, Mahon, Co. Cork, T12 W7CV Ireland, www.eirechrom.ie
    • Eppendorf, Hamburg, Germany, www.eppendorf.com/US-en/
    • ESI Ultrapure, Cwmbran, Torfaen, NP44 3XS, UK, www.esitechgroup.com
    • Finesse Solutions, Santa Clara, CA 95054, www.finesse.com
    • GE Healthcare's Life Sciences Business, Pittsburgh, PA 15264, www.gelifesciences.com/webapp/wcs/stores/servlet/catalog/en/GELi feSciences-us/brands/xcellerex
    • Hamilton Robotics, Bonaduz, Switzerland, www.hamiltoncompany.com
    • Holland Applied Technologies, Burr Ridge, IL 60527, http://www.hollandapt.com
    • Millipore, Millipore Sigma, Burlington, MA 01803, www.emdmillipore.com
    • NewAge Industries, Southampton, PA 18966, www.newageindustries.com
    • Pall Biotech, Port Washington, NY 11050, https://biotech.pall.com
    • Parker Hannifin, Cleveland, OH 44124, www.parker.com
    • PBS Biotech, Camarillo, CA 93012, www.pbsbiotech.com
    • PendoTech, Princeton, NJ 08542, www.pendotech.com
    • PerfuseCell A/S, DK-2840 Holte, Denmark, www.perfusecell.com
    • PreSens Precision Sensing, 93053 Regensburg, Germany, www.presens.de
    • ProlifeCell, DK-2840 Holte, Denmark, www.prolifecell.com/product
    • PumpCell A/S, DK-2840 Holte, Denmark, www.pumpcell.com
    • Refine Technology, Pine Brook, NJ 07058, www.refinetech.com
    • Sartorius AG, Goettingen, Germany, www.sartorius.com
    • Stobbe Tech, DK-2840 Holte, Denmark, www.stobbe.com/research/biotech/glycocell
    • Sysbiotech, Perigny France, www.sysbiotech.eu
    • Thermo Fisher Scientific, Waltham, MA 02451, www.thermofisher.com/us/en/home/lifescience/ bioproduction/single-use-bioprocessing.html
    • Zeta Holding, Graz, Austria, www.zeta.com

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